

Novel Flow Solutions in Urology and Vascular Disease
Our Products
Noninvasive Urethro-Cystometer(NUC): A device for differential diagnosis of Lower Urinary Tract Symptoms (LUTS) in the elderly male. Licensed to a medical device company and currently being marketed.
The Biofluid Inflammometer™ - Advancing Physiologic Measurement to Improve Understanding of Human Disease:
Biofluid Technology, Inc. develops investigational measurement platforms designed to characterize the physical and functional properties of blood and their relationship to human physiology and disease.
Many aspects of human disease—particularly those involving inflammation and cardiometabolic dysfunction—are currently assessed through biochemical markers alone. While valuable, these measurements do not directly capture how blood behaves within the circulation or how changes in its properties may affect tissue perfusion and organ function.
Biofluid Technology is developing technologies to address this gap by enabling quantitative characterization of whole blood behavior under physiologically relevant conditions. These platforms are intended to support improved understanding of the relationship between blood flow properties, microcirculatory dynamics, and systemic disease states.
Technology Focus:
Our work is centered on the development of investigational physiologic measurement systems that:
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Characterize whole blood properties across defined operating conditions
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Generate reproducible, quantitative datasets suitable for analysis
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Support integration with clinical and laboratory data
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Enable future development of data-driven interpretation frameworks
Current Development Efforts:
Biofluid Technology is currently focused on preclinical validation and risk reduction of its investigational platforms. Ongoing work includes:
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Measurement reproducibility and repeatability assessment
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System performance characterization under controlled conditions
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Evaluation using fresh human whole blood samples
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Refinement of operational and analytical workflows
These efforts are intended to establish a robust technical and translational foundation prior to clinical evaluation.
Pipeline:
Our current development portfolio includes:
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The Biofluid Inflammometer™ – an investigational whole blood viscometry platform
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Additional technologies under development focused on physiologic measurement and device-based assessment
Important Notice:
All technologies under development by Biofluid Technology, Inc. are investigational and are not currently approved for diagnostic or clinical use.
Disclaimer: The medical devices described herein are limited by federal (U.S.) law to investigational use. They have not yet been approved for clinical diagnostic application.
About Us
BioFluid Technology is a development-stage medical device company established in 2010. Based on technology and expertise from scientists at the University of Pennsylvania, BioFluid Technology is focused on the research and development of patented physiologic measurement and diagnostic-enabling technologies designed to characterize the physical properties and flow characteristics of biological fluids.
Contact Us
BioFluid Technology Inc.
337 Fishers Road
Bryn Mawr, PA 19010
(610) 527-4530
Preferred Contact:
reuben.kron@biofluidtechnology.com
References

Urological Cystometry
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Noninvasive techniques for the measurement of isovolumetric bladder pressure. Blake C, Abrams P. J Urol. 2004 Jan;171(1):12-9.
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Noninvasive methods of diagnosing bladder outlet obstruction in men. Part 2: Noninvasive urodynamics and combination of measures. Belal M, Abrams P. J Urol. 2006 Jul;176(1):29-35.
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Positioning invasive versus noninvasive urodynamics in the assessment of bladder outlet obstruction. Arnolds M, Oelke M. Curr Opin Urol. 2009 Jan;19(1):55-62.
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Review of invasive urodynamics and progress towards non-invasive measurements in the assessment of bladder outlet obstruction. Griffiths CJ, Pickard RS. Indian J Urol. 2009 Jan;25(1):83-91.
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Non-invasive urodynamics predicts outcome prior to surgery for prostatic obstruction. Losco G, Keedle L, King Q. BJU Int. 2013 Nov;112 Suppl 2:61-4.
Cardiovascular Viscometry
Viscometry and COVID-19
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Maier, CL., Truong, AD., Auld, SC., Polly, DM., Tanksley, CL., Duncan, A. COVID-19-associated hyperviscosity: a link between inflammation and thrombophilia? Lancet. 2020, Jun 6;395(10239):1758-1759
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Ahmed, S., Zimba, O., Gasparyan, AY. Thrombosis in Coronavirus Disease 2019 (COVID-19) through the prism of Virchow's triad Clin Rheumatol 2020, Sep;39(9):2529-2543.
(under development)
Specialty Areas
Urology
Hematology
Rheumatology
Laboratory Medicine
Internal Medicine
Primary Care
Infectious Disease
Cardiovascular Disorders