Disclaimer: The medical devices described herein are limited by federal (U.S.) law to investigational use. They have not yet been approved for clinical diagnostic application.
Novel Flow Solutions in Urology and Vascular Disease
Noninvasive Urethro-Cystometer: A device for differential diagnosis of Lower Urinary Tract Symptoms in the elderly male. Licensed to a medical device company and currently being marketed.
Blood and Blood Plasma Viscometer: A device for differential diagnosis of inflammatory and hematologic disorders. Useful in the management of COVID-19.
BioFluid Technology is a development stage medical device company established in 2010. Based on technology and expertise from scientists at the University of Pennsylvania, BioFluid Technology is focused on the research and development of patented diagnostic devices that measure the physical properties and flow characteristics of biological fluids.
BioFluid Technology Inc.
337 Fishers Road
Bryn Mawr, PA 19010
Noninvasive techniques for the measurement of isovolumetric bladder pressure. Blake C, Abrams P. J Urol. 2004 Jan;171(1):12-9.
Noninvasive methods of diagnosing bladder outlet obstruction in men. Part 2: Noninvasive urodynamics and combination of measures. Belal M, Abrams P. J Urol. 2006 Jul;176(1):29-35.
Positioning invasive versus noninvasive urodynamics in the assessment of bladder outlet obstruction. Arnolds M, Oelke M. Curr Opin Urol. 2009 Jan;19(1):55-62.
Review of invasive urodynamics and progress towards non-invasive measurements in the assessment of bladder outlet obstruction. Griffiths CJ, Pickard RS. Indian J Urol. 2009 Jan;25(1):83-91.
Non-invasive urodynamics predicts outcome prior to surgery for prostatic obstruction. Losco G, Keedle L, King Q. BJU Int. 2013 Nov;112 Suppl 2:61-4.
Viscometry and COVID-19
Maier, CL., Truong, AD., Auld, SC., Polly, DM., Tanksley, CL., Duncan, A. COVID-19-associated hyperviscosity: a link between inflammation and thrombophilia? Lancet. 2020, Jun 6;395(10239):1758-1759
Ahmed, S., Zimba, O., Gasparyan, AY. Thrombosis in Coronavirus Disease 2019 (COVID-19) through the prism of Virchow's triad Clin Rheumatol 2020, Sep;39(9):2529-2543.
Garcia, Luis F. 2020 Immune Response, Inflammation, and the Clinical
Spectrum of COVID-19. Front Immunol Jun 16;11:1441.
McFadyen JD, Stevens H, Peter K. 2020 The Emerging Threat of
(Micro)Thrombosis in COVID-19 and Its Therapeutic Implications. Circ Res. Jul 31;127(4):571-587.
Goshua G, et. al., 2020 Endotheliopathy in COVID-19-associated coagulopathy: evidence from a single-centre, cross-sectional study. Lancet Haematol. Aug;7(8):e575-e582.
White D, et. al., 2020 Heparin resistance in COVID-19 patients in the intensive care unit. J Thromb Thrombolysis. Aug;50(2):287-291.
Watson J, Jones HE, Banks J, Whiting P, Salisbury C, Hamilton W. 2019 Use of multiple inflammatory marker tests in primary care: using Clinical Practice Research Datalink to evaluate accuracy. Br J Gen Pract. Jul;69(684):e462-e469.